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Hatice Yıldırım Selected Research

Plastoquinone

10/2022In Vitro Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with In Silico Insights.
8/2022In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells.
6/2022Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction.
1/2022In Vitro and In Silico Study of Analogs of Plant Product Plastoquinone to Be Effective in Colorectal Cancer Treatment.
11/2021Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells.
12/2019Discovery and structure-activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells.

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Hatice Yıldırım Research Topics

Disease

9Neoplasms (Cancer)
11/2023 - 04/2019
3Breast Neoplasms (Breast Cancer)
08/2022 - 11/2021
2Necrosis
06/2022 - 12/2019
2Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 10/2015
2Carcinogenesis
01/2018 - 10/2015
1Prostatic Neoplasms (Prostate Cancer)
11/2023
1Infections
01/2022
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2019
1Uterine Cervical Neoplasms (Cancer of the Cervix)
04/2019
1Ulcerative Colitis
10/2015

Drug/Important Bio-Agent (IBA)

6PlastoquinoneIBA
10/2022 - 12/2019
3quinone (benzoquinone)IBA
09/2023 - 08/2021
3Biomarkers (Surrogate Marker)IBA
04/2019 - 10/2015
2Antineoplastic Agents (Antineoplastics)IBA
11/2021 - 12/2019
26-anilino-5,8-quinolinedioneIBA
08/2021 - 01/2021
2Imatinib Mesylate (Gleevec)FDA Link
08/2021 - 12/2019
2alkoxyl radicalIBA
01/2021 - 11/2019
1Proteins (Proteins, Gene)FDA Link
11/2023
1Benzocaine (Americaine)FDA Link
08/2022
1Dihydrotachysterol (AT 10)IBA
08/2022
1thiazolyl blueIBA
08/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
06/2022
1VancomycinFDA LinkGeneric
01/2022
1phenylpiperazineIBA
11/2021
1Guanylate Cyclase (Guanylyl Cyclase)IBA
01/2021
1BoronIBA
04/2019
1Aurora Kinase AIBA
10/2015
1Phosphotransferases (Kinase)IBA
10/2015

Therapy/Procedure

2Therapeutics
11/2023 - 11/2021